I would say it depends on several things. Weight of the car, type of 5 speed, purpose of the car(street or strip), what rpm you shift at,..etc...
My old DSS 331 (10.5:1, AFM N-91 cam, AFM stage 3 TW'S, parker funnel web,AED 850ho carb,etc...)ran great on the street and strip with 4.56's and...