351w with a t trim doesnt run right

Go to a professional tuner and have him tune it ON a dyno. Hard to get into anymore detail cause your post was pretty vague

I'm running a 408W with a t trim, 72 lb injectors. I'm tuning with a Tweecer and a wide band. Even though the 95mm PMAS MAF was setup up for the 72 lb injectors, a small voltage drop with the electric radiator fan starting upset the idle.

I tune will be needed to idle correct as well as to get the most power and still be safe.

Did you have any issues with hood clearance with the Vortech on that 351w block?