Make sure your hoses and coolant are good. Carry a spare belt. I used to live in Philly. I moved to FL in 1988. I make that drive a lot. I driven it in all kinds of weather. The 5.0L was made to run on the highway. At least that is how I felt. The Carolina's will seem like the longest part, its about 360 miles to go through them. Georgia will be the shortest state, only 108 miles via I-95. Orlando traffic sucks, but you will be getting off at either SR 434 or SR 436 to head to Apopka.
Good luck and safe travels.
Good luck and safe travels.