Drivetrain Help Deciding Between 4.10s And 3.73

I have 4:10s in my 4.6 with FI and can say it really wakes the car up. You will have to shift more (but not every two seconds), but for me it was not really that big a deal, just makes the car more fun to drive. I would think for a V6, the 4:10s would best if you are looking for the best acceleration. Not sure what gears you have now. If you have 3:55s now, going to 3:73s is not that big a change for the money spent. I believe at 85 mph you would probably be in the 2500 to 3000 rpm range in high gear with 4:10s depending on the diameter of you rear tires.

The 4.10 is the optimum gear for the V6 and in 5th gear on stock tires, the engine would be turning at ~2500rpm at 70mph.