There is nothing wrong with a 408 or a 4" stroke motor, yes it has a little more side loading but there are some factory set-ups with worse rod ratios.
It depends on your budget, personally I'd go 408ci (20-22cc dish piston will get you about 10.5:1 with a 58cc head), a good 200cc+ head and then match the rest of the components not surte if your staying EFi or carb.
What kind of budget do you have??? Don't forget about the rest of the component in your car, chassis, suspension, driveline, fuel system, etc....all of these need to be looked at for a reliable 10 sec car.