4.10's on a mildly to heavy modded car would get you into trouble as the ratio is so steep you would break the tires loose everytime. 3.73's are good for a lightly modded car/ YOu might even want to consider 3.55's instead which would be about the middle of the road.
On my 98 manumatic, the 4.10's constantly cause the rear tires to break loose from 1-2 gear, and sometimes 2-3 gear, and that's with only ram air, axhaust, and shift kit.