I've been doing some research on different heads in the last week (which sucks, cause' I just found out my head aren't "P's"). I haven't seen or heard of many people using the E5's.... and I've seen nothing on them as far as flow charts or valve sizes.
One's things for sure, though.... if it was me, I'd find a way to steepen compression with those things.... whether by piston choice or milling them. Unless you're planning for some boost.... 69cc seems a bit much.