If you have no ignition key at all, you do need to drill out the lock pin holding the cylinder in the column. You might be money ahead to have a mobile locksmith rekey the lock if he can.
I haven't had a lock on a car rekeyed but have taken a new ignition lock to a locksmith for a rekey and it was about 15 bucks (with a couple of extra keys) IIRC.
I'd call the locksmiths and weigh this option vs busting your old lock and buying a new one (which will need a rekey if you want to only have one key for the car).
Good luck.