Kilgore is right, but I doubt you had any intention of using the spray on the public roads
Some people choose to go direct port with nitrous because it IS the safest option. With direct port, the nitrous is sprayed evenly into each intake runner, making sure each cylinder gets the same amount of nitrous and fuel. If one cylinder recieves more nitrous than the others, your engine could be at risk.
The next safest system would be a wet kit. Fuel and nitrous are both mixed together and spraying into the intake tubing and sucked into the engine. The problem is, 4.6L intake manifolds don't like too much fuel or nitrous. If fuel "puddles" in the intake, or nitrous, then the intake explodes, almost always damaging hoods or even worse, the cylinder heads. This can be prevented by buying a non-plastic intake for your GT. You can also buy safety features for your set up to prevent this from happening.
On stock internals, the biggest shot I would do personally is a 100 shot. Our pistons and rods can't handle much more than 375-400WHP. And the bigger the shot, the more chance you have of blowing your intake. So if you DO get a 100 shot, be sure to have the car tuned on the dyno. You want your AF ratio perfect so the car doesn't run lean.
If your running a 100 shot, I would highly recommend an upgraded fuel pump as well. Such as a SVT Ford Focus pump, or GT40 fuel pump.
I think your stock pump could handle a 75 shot. Just be sure you run the highest octane gas you can. Here in CA I can only get 91

. You will also need 2 step colder plugs such as NGK tr6's or Autolite 103's.
I highly recommend you get these safety features as well: window switch, WOT switch, fuel pressure safety switch, fuel pressure gauge, nitrous pressure gauge.
I hope this helps you out. Just be sure you do tons of research before you decide to spray. And before you even think about spraying, get your car compression tested and monitor the oil pressure with an aftermarket gauge. Feel free to ask questions
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