manifold vacuum is inversely proportionate to how far the throttle is open per delta-time.
E.g., at WOT, there's almost no vacuum.
But at WOT, there's the most crankcase pressure - that will test the flowing ability of your crankcase ventillation. The screen/baffle for the intake helps a lot.
Do you use a fuel filter type of inline filter, or a separator? The trap in the separator helps keep oil from being scavenged and recirculated at WOT.