Running too small of an injector is asking for trouble, and running too big of an injector is only going to hurt the cars performance. If you run a 42 lb/hr injector on a normal H/C/I 302 combo, your going to have to turn the fuel pressure down to a point where it's going to mess up the spray pattern/atomization of the fuel. This is not good.
A 24 lb/hr injector is good for 400 flywheel horsepower. Upgrading to a 24 lb/hr injector with the basic mods such as an intake manifold, exhaust, MAF, pulleys, etc. is not a bad idea. Sure, it's definitely not worthwhile from a pure horsepower stand point, but if you plan on going further, you're going to have to buy the new injectors anyhow.
Joe