Engine Help timing possibly

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Good evening,

I hope all is well. I installed a new Edelbrock intake manifold I also changed out spark plugs, spark plug wires, distributor cap and rotor screw. My question is would a new aftermarket intake manifold effect my timing ?... Next I checked my distributor advance and I used my mityvac when I pump it holds nothing so I'm assuming it's bad... This is all because after I put the new intake manifold on when I let my clutch out and give gas it sounds like it's sorta missing and when going up any type of hill it wanna cut out and sound like a backfire.. any help ?
 
You have to remove the distributor when putting on the lower intake manifold, correct? Maybe you put it back in a tooth or so off? Did you make sure the lower was all torqued properly and sealed?
 
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