Hypothetical?

Route666 said:
Compression ratio takes back some of what big cames take out of the low-end though right? So if you were to up CR, you could up the cam even more and have the same change in low-end as you would have with a smaller cam and no CR increase, but also more high-end power.

Just chucking in an extra factor to cam choice.

one thing you always have to be carefull with regards to dynamic cylinder pressure. if the cam has enough duration and or valve overlap, you can get by with raising the compression ratio up to a full point, from around 9.5 to about 10.5:1, and you can avoid detonation. you may not even have to raise the octane level of the gas you use. ignition timing also plays a part in all this as well.
 
Yeh that's the benefit I see, you can up the CR by using a BIGGER cam, which lessens your dynamic CR at low rpm, but increases it at high rpm where detonation is less of an issue as the engine is turning so fast anyway. Seems like a win-win combination, no need for higher octane or less ignition, to an extent.