Would you say that it is loud to the point that it would be annoying, or attract unwanted police attention?
The way inspection is done obviosuly varies from state to state. Where I live in IL they only test OBD2 cars, and all they do is plug their scanner into it and see if any monitors are failed or not run. You are allows to have one monitor not ready. If you have a tune that turns off the rear 02s, the catalst monitor will not be run, but since every other monitor is fine, and the MIL is not illuminated, you will pass. My brother's LS1 has longtubes, offroad Y pipe/catback, LS6 intake, EGR delete, throttle body, bigger MAF, and a tune, and he pled right in, passed, and was on his way.