LT's can cause problems two ways. First, the EEC is expecting feedback from the O2 sensors more quickly than it gets when you have LT's installed. That is fixable with a chip. Second, most LT's put the O2 sensors far enough way that they don't run hot enough, especially if the ambient temperature is fairly cool (say 50*). This makes them read lean, which causes the EEC to add fuel trying to correct a lean condition that doesn't really exist.
If you have to deal with strict emissions, they could cause you some grief. Otherwise it'd probably work out okay.