You can actually run stock pistons with Twisted Wedge heads. Really, it all depends on how much lift you're planning on running, but for a mild cam (TFS Stage 1, FRPP alphabet cam, etc), you're plenty safe on the stockers, or a stock replacement. Several companies do sell pistons with valve reliefs cut for the Twisted Wedge heads, if you'd really prefer to go that route, but it's not absolutely necessary. The TFS heads are the only ones that can get away with no flycutting with a 2.02 inch intake valve because of the canted valves, instead of being an inline setup like AFR, Edelbrock, etc.