running out of fuel??

If you're talking about what's in your sig, it's quite possible you're running lean at higher RPMs. I'm certainly not the fuel system expert but that seems like a good guess to me. You didnt list anything about what fuel pump or regulator youre using in your sig, is it all stock? What kind of numbers is your motor making? You might in all seriousness need to upgrade your whole fuel system if you're making big numbers. It's not uncommon for the stock fuel lines to just not be able to carry enough fuel for the motor at high RPMs. As for the pump, my old 351W ran off of a Holly Red, but fell flat at the quarter because it ran lean...so i think you hit the nail on the head with this one.

I'd check the fuel filter and all that BS first before you start throwing parts on. But, if you have a stock pump i'd put that down on your upgrade list ASAP even if the filter is clean. You may want to get some dyno time if you havent, that way you can sort out the best AF ratio for the higher RPMs and dial in your fuel pressure.

Yeah. It doesn't sound like an ignition problem. I would check the basics like 85_SS_302_Coupe said first. Did it just start doing this? Has it run ok in the past with the same combo?

If you still have the old TFI module on the distributor, it is suspect. The stock TFI often gets hot and fails to work at high RPM. The result is an engine that runs strong and then seems to quit at RPM above 4000.