Supercharger tune question

I'm curious if I put on a supercharger with 60 lb injectors, a slot style MAF in a blow thru 3" housing and have it all tuned to work nicely together, can i remove the supercharger and run the same MAF and injectors without retuning?

Retrofit the MAF into a lightning housing and slide it into a cold air kit.

Will she run or does it require a retune?

I follow that. My question is whether a car that had been tuned to accept the injectors and maf with a supercharger can operate correctly without the supercharger.

The existing tune would account for the different injectors and maf. But the significant change would be the removal of the supercharger from the vehicle and the same maf being moved to a different housing and location. Plus the maf would now be a draw thru in NA form, as opposed to being used as blow thru in the supercharged setup.