Under vacuum conditions, engine vacuum sucks on the crankcase through the pcv valve. It pulls any blowby into the intake manifold. Because you don't want to create a vacuum in the crankcase, there has to be a path to LET METERED AIR INTO the crankcase. That's what the little hose between the throttle body and the valve cover nipple are for. Under high manifold vacuum, metered air travels from the throttle body to the crankcase through the valve cover nipple. Some people who remove the hose and cap off those openings hear squealing sounds under vacuum as air gets pulled into the crankcase past the front or rear seals.
At w.o.t., there is crankcase pressure, and atmospheric pressure in the intake manifold - no vacuum. If the crankcase pressure is greater than the manifold pressure then crankcase venting will occur through the pcv valve/line AND through the valve cover to throttle body line. You can now see that the throttle body to valve cover line is bi-directional. Under some circumstances, air moves from the t/b to the crankcase; under other circumstances air moves from the crankcase through the throttle body. At part load when there is low manifold pressure and low blowby (crankcase pressure) the differential can't overcome the small check valve in the pcv, so venting of the crankcase occurs through the valve cover to throttle body line.
That's what that hose is for. There is absolutely no performance benefit to disconnecting/capping it off - and it may be detrimental. If you have a functioning pcv hooked to manifold vacuum, I'd hook it back up. For breathered valve covers, it's unnecessary.
this is a copy of a post from or own Mr Yount.