Like anything else, it depends on the whole combo, cams only controll the lift of the valves. The cam is ground to promote cylinder filling at certian engine speeds and many different things determine the grind to do that. So a cam engineered to operate from 4000rpm to 7000rpm was not engineered to operate at 800rpm, so of course it won't run right. Lets say that cam was engineered for a 408, it won't do the same thing in a 306.