I made SEVERAL runs on a 150 wet shot with no timing adjustment,just premium gas and a bottle of octane booster in the tank. I had no problems until I accidently let the bottle pressure get too high and burnt a valve. I think you should run 2-step colder plugs,and get yourself a rpm window switch. Set the shut off rpm to about 58-5900,well below the factory rev limiter(it cuts off fuel to limit rpm). Also a fuel pressure guage to monitor what happens during a full 1/4 mile run. You may have a weak or bad fuel pump and when the pressure drops to much you're going to run WAY too lean,burn plugs and get backfires.
For those that automaticaly say you can't safely run a 150 shot-WRONG. I personally have done it(for a period of 2 years) & would see no problem with anyone else,AS LONG AS YOU DO THINGS BY THE BOOK!!!! If you want to play around then don't run any bigger than a 100. 150 is not to much for the engine,trans or car to handle but it leaves less room for error. You must monitor your fuel pressure,your bottle pressure,run good gas with octane booster,run 2 step colder plugs,and have a rpm window switch/fuel pressure cutoff switch for safety.