Skipping V6

Alright guys and girls any ideas will be appreciated. I have replaced my plugs,wires,coil pack,air filter, and my fuel filter. I have a 2002. It does not skip alot but its is skipping in second gear mostly. It is really getting annoying. If anyone has had this problem before please let me know how to remedy it. Also I am having a noise like a high pressure air hose being disconnected from an air tool. This happens between 3-4k RPM. Someone has to have had this problem....HELP!!!!