That's a broad question to answer. Ford made small changes in the harnesses year by year so that they don't really interchange with each other. It's not a speed density harness vs mass air, but rather 1990 harness, 1991 harness, etc.
Some of the individual wires route differently. For the most part if you want to swap to mass air you'll need a conversion harness, and also pay attention to the O2 sensor jumper pinout